Cryo-EM Center



GPCR Structure-Based Drug Discovery (SBDD)

We will generate project progress reports at every step of the project

1.Sequence alignment at molecular cloning stage


2.Protein purity uation by SDS-PAGE and size-exclusion chromatography


3.Negative staining for protein homogeneity and particle integrity



4.Structure determination

                       Lei Wang, et al., Cell Res., 2021